Skip to content Learn about the access keys available for Aristotle.Cloud

Definition

The histopathological grade or differentiation in a person with cancer, as represented by a code.

Components

Data Element (this item)

Representation

This representation is based on the value domain for this data element, more information is available at " Histopathological grade code N ".
Data Type Number
Format N
Maximum character length 1
Values
Value Meaning Start Date End Date
Permissible Values 1 Grade 1: Low grade; well differentiated, differentiated, NOS
2 Grade 2: Intermediate grade, moderately differentiated, moderately well differentiated, intermediate differentiation
3 Grade 3: High grade, poorly differentiated
4 Grade 4: Undifferentiated, anaplastic
Supplementary Values 9 Grade or differentiation not determined, not stated or not applicable

Comments

Guide for use:

Histopathological grade or differentiation describes how little the tumour resembles the normal tissue from which it arose.

Only malignant tumours are graded and only one code can be recorded.

When more than one grade is documented for the primary tumour within the same specimen report, use the highest grade. For example, if grade 2-3 is documented, record the grade as 3.

If the grades differ on multiple pathology reports for the same tumour, use the value from the larger specimen (for example, the grade from a surgical excision specimen would be used over the grade from a specimen from a diagnostic biopsy).

Breast cancer coding rules:

Use the Nottingham grade (Elston-Ellis modification of Bloom-Richardson grading system). This classification only uses grades 1-3, 9.

For an invasive tumour with an in situ component, record the grade for the invasive component only. If the grade of the invasive component is not reported, record the grade as unknown.

Origin:

World Health Organization

Commission on Cancer American College of Surgeons

References

Fritz A et al. 2000. International Classification of Diseases for Oncology, Third edition (ICD-O), 3rd edition. Geneva: World Health Organization

American College of Surgeons 1998. Standards of the Commission on Cancer Registry Operations and Data Standards (ROADS), Volume II, Commission on Cancer

Johnson CH & Adamo M (Editors) 2007. SEER Program Coding and Staging Manual 2007. MD 2007. Bethesda: National Cancer Institute, NIH Publication number 07-5581
This content Based on Australian Institute of Health and Welfare material. Attribution provided as required under the AIHW CC-BY licence.

Related content

Relation Count
Input in Derivations 0
Output in Derivations 0
Inclusion in Data Set Specifications 2
Inclusion in Data Distributions 0
As a numerator in an Indicator 0
As a denominator in an Indicator 0
As a disaggregation in an Indicator 0