Definition
Immunohistochemistry is a technique used in the evaluation of pathology specimens to analyse and identify cell types based on the binding of antibodies to specific components (antigens) of the cell. The antigens are demonstrated in tissues by the use of markers that are either fluorescent dyes or enzymes such as horseradish peroxide.
Immunohistochemistry may be useful, for example, to distinguish between primary and metastatic tumours, identify where the tumour originated if the primary is unknown, and help reach a diagnosis when there is limited biopsy material available for morphological assessment.References
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