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The date of first recurrence as distant metastatic disease.

The term recurrence defines the return, reappearance or metastasis of cancer (of the same histology) after a disease-free intermission or remission.

Distant metastasis refers to the spread of cancer of the same histology as the original (primary) tumour to distant organs or distant lymph nodes.


American College of Surgeons 1998. Standards of the Commission on Cancer: Registry Operations and Data Standards (ROADS), Volume II, Commission on Cancer
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