Whether the multiple primary tumours in the person with cancer are synchronous or metachronous.Synchronous primary tumours are detected simultaneously, either preoperatively or in the resected specimen. Metachronous primary tumours are detected after a time interval between detection of the first lesion and detection of a subsequent primary lesion.
Breathnach OS & Skarin AT 2009. Multiple primary lung cancers. Wolters Kluwer Health, UpToDate Inc., Waltham, MA. Viewed 8 March 2011,
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